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CDNF 抗体

This anti-CDNF antibody is a 小鼠 单克隆 antibody detecting CDNF in WB, ICC, IHC (p), IF 和 EIA. Suitable for 人.
产品编号 ABIN5540986
发货至: 中国

Quick Overview for CDNF 抗体 (ABIN5540986)

抗原

See all CDNF 抗体
CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CDNF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

克隆位点

7G5
  • 特异性

    Recognizes Human CDNF and not Mouse CDNF. Other species not tested.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Recombinant Human CDNF produced using CHO-based. Antigen is purified from cell culture supernatant.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/5000-1/10000. Western Blot: 1/1000-1/4000. Immunofluorescence: 1/100-1/300. Immunohistochemistry on Paraffin Sections: 1/100-1/200. Formalin-fixed, paraffin-embedded tissues requires antigen retrieval.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.4 Preservatives: 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

    别名

    cdnf

    背景

    CDNF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007 Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.

    UniProt

    Q49AH0
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